論文業績一覧


 

2021

査読付論文

Fukumura R, Sukhbaatar A, Mishra R, Sakamoto M, Mori S, Kodama T. Study of the physicochemical properties of drugs suitable for administration using a lymphatic drug delivery system. Cancer Sci. 2021 May;112(5):1735-1745.

Kato S, Yoshiba S, Mori S, Kodama T. Optimization of the Delivery of Molecules into Lymph Nodes Using a Lymphatic Drug Delivery System with Ultrasound. Int J Pharm. 2021 Mar 15;597:120324.

Yasukawa Y, Nozawa K, Tiittanen T, Karppinen M, Lindén J, Shirsath S.E, Yabukami S. Dynamical magnetic behavior of anisotropic spinel-structured ferrite for GHz technologies. (2021) Scientific Reports, 11 (1):614.

Shikano A, Tonthat L, Yabukami S. A Simple and High-Accuracy PID-Based Temperature Control System for Magnetic Hyperthermia Using Fiber Optic Thermometer. (2021) IEEJ Transactions on Electrical and Electronic Engineering, 16 (5):807-809.

Tonthat L, Mitobe K, Yabukami S. Development of an Automatic Localization System of Magnetic Particles for Hyperthermia Therapy. (2021) IEEE Transactions on Magnetics, 57 (2), 9138439.

Yabukami S, Nozawa K, Tonthat L, Okita K, Sai R. Impact of Complex Permeability Measurements up to Millimeter-Wave Frequency Range. (2021) IEEE Transactions on Magnetics, 57 (2),9149663.

2020

査読付論文

Kato S, Takeda K, Sukhbaatar A, Sakamoto M, Mori S, Shiga K, Kodama T. Intranodal pressure of a metastatic lymph node reflects the response to lymphatic drug delivery system. Cancer Sci. 2020 Sep 3;111:4232–4241.

Kato S, Shirai Y, Motozono C, Kanzaki H, Mori S, Kodama T. In vivo delivery of an exogenous molecule into murine T lymphocytes using a lymphatic drug delivery system combined with sonoporation. Biochem Biophys Res Commun. 2020 Mar 13.

Tonthat L, Yamamoto Y, Mitobe K, Yabukami S. Effect of applied magnetic field on permeability and heating efficiency of multifunctional micro/nano-magnetic particles for hyperthermia therapy. (2020) AIP Advances, 10 (12):125324.

2019

査読付論文

Sukhbaatar A, Sakamoto M, Mori S, Kodama T. Analysis of tumor vascularization in a mouse model of metastatic lung cancer. Sci Rep. 2019 Nov 5;9(1):16029.

Kato S, Shirai Y, Sakamoto M, Mori S, Kodama T. Use of a lymphatic drug delivery system and sonoporation to target malignant metastatic breast cancer cells proliferating in the marginal sinuses. Scientific Reports. 2019 Sep 13;9(1):13242.

Izumiyama T, Mori Y, Mori S, Mori N, Kodama T, Itoi E. The effect of anti-IL-6 receptor antibody forthe treatment of McH-lpr/lpr-RA1 mice that spontaneously developed destructivearthritis and enthesitis. BMC Musculoskeletal Disorders. 2019; 20:286.

Kikuchi R, Sukhbaatar A, Sakamoto M, Mori S, Kodama T. A model system for studying superselective radiotherapy of lymph node metastasis in mice with swollen lymph nodes. Clin Transl Radiat Oncol. 2019 May 18;20:53-57.

Fujii H, Horie S, Sukhbaatar A, Mishra R, Sakamoto M, Mori S, Kodama T. Treatment of false‐negative metastatic lymph nodes by a lymphatic drug delivery system with 5‐fluorouracil. Cancer Med. 2019 May;8(5):2241-2251.

Iwamura R, Sakamoto M, Mori S, Kodama T. Imaging of the mouse lymphatic sinus during early-stage lymph node metastasis using intranodal lymphangiography with X-ray micro-computed tomography. Mol Imaging Biol. 2019 Oct;21(5):825-834.

Sukhbaatar A, Mori S, Saiki Y, Takahashi T, Horii A, Kodama T. Lymph node resection induces the activation of tumor cells in the lungs. Cancer Sci. 2019 Feb;110(2):509-518.

Tonthat L, Takahashi S, Onodera H, Okita K, Yabukami S, Yokota K, Furuya M, Kanetaka H, Miura Y, Takahashi H, Watanabe Y, Akiyama R. A simple and rapid detection system for oral bacteria in liquid phase for point-of-care diagnostics using magnetic nanoparticles. (2019) AIP Advances, 9 (12):125325.

2018

査読付論文

Kodama T, Mori S, Nose M. Tumor cell invasion from the marginal sinus into extranodal veins during early-stage lymph node metastasis can be a starting point for hematogenous metastasis. J Cancer Metastasis Treat. 2018;4:56.

Ouchi T, Sukhbaatar A, Horie S, Sakamoto M, Shiga K, Mori S, Kodama T. Superselective Drug Delivery Using Doxorubicin-Encapsulated Liposomes and Ultrasound in a Mouse Model of Lung Metastasis Activation. Ultrasound Med Biol. 2018 Aug;44(8):1818-1827.

Zheng J, Jia L, Mori S, Kodama T. Evaluation of metastatic niches in distant organs after surgical removal of tumor-bearing lymph nodes.BMC Cance. 2018 May 30;18(1):608.

Fujii H, Horie S, Takeda K, Mori S, Kodama T. Optimal range of injection rates for a lymphatic drug delivery system. J Biophotonics. 2018 Aug;11(8):e201700401.

Jadhav M, Kalhapurea RS, Rambharose S, Mocktar C, Singh S, Kodama T, Govender T. Novel lipids with three C18-fatty acid chains and an amino acid head group for pH-responsive and sustained antibiotic delivery. Chem Phys Lipids. 2018 Jan 2;212:12-25.

2017

査読付論文

Ncapayi V, Sundararajan P, Songca SP, Kodama T, Oluwafemi OS. Green synthesis of MPA-capped CdTe/CdSe quantum dots at different pH and its effect on the cell viability of fibroblast histiocytoma cells. Materials Letters. 2017; 209: 299-302.

Tada A, Horie S, Mori S, Kodama T. Therapeutic effect of cisplatin given with a lymphatic drug delivery system on false-negative metastatic lymph nodes. Cancer Sci. 2017 Nov;108(11):2115-2121.

Oladipo AO, Oluwafemi OS, Songca SP, Sukhbaatar A, Mori S, Okajima J, Komiya A, Maruyama S, Kodama T. A novel treatment for metastatic lymph nodes using lymphatic delivery and photothermal therapy. Sci Rep. 2017 Apr 3;7:45459.

Mikada M, Sukhbaatar, A, Miura Y, Horie S, Sakamoto M, Mori S, Kodama T. Evaluation of the enhanced permeability and retention effect in the early stages of lymph node metastasis. Cancer Sci. 2017 May;108(5):846-852.

Takeda K, Mori S, Kodama T. Study of fluid dynamics reveals direct communications between lymphatic vessels and venous blood vessels in lymph nodes of mice. J Immunol Methods. 2017 Jun;445:1-9.

Matsuki D, Oladipo A, Horie S, Okajima J, Komiya A, Oluwafemi O, Maruyama S, Mori S, Kodama T. Treatment of tumor in lymph nodes using near-infrared laser light-activated thermosensitive liposome-encapsulated doxorubicin and gold nanorods. J Biophotonics. 2017 Dec;10(12):1676-1682.

Sato T, Takemura T, Ouchi T, Mori S, Sakamoto M, Arai Y, Kodama T. Monitoring of blood vessel density using contrast-enhanced high frequency ultrasound may facilitate early diagnosis of lymph node metastasis. J Cancer. 2017 Feb 25;8(5):704-715.

Ncapayi V, Parani S, Songca SP, Kodama T, Oluwafemi OS. Simple green synthesis of amino acid functionalised CdTe/CdSe/ZnSe core-multi shell with improved cell viability for cellular imaging. Materials Letters. 2017;189:168-71.

Mori N, Mugikura S, Takahashi S, Ito K, Takasawa C, Li L, Miyashita M, ko Kasajima A, Mori Y, Ishida T, Kodama T, Takase K. Quantitative analysis of contrast-enhanced ultrasound imaging in invasive breast cancer: a novel technique to obtain histopathological information of microvessel density. Ultrasound Med Biol. 2017 Mar;43(3):607-614.

2016

査読付論文

多田明日香,堀江佐知子,森士朗,小玉哲也. リンパ行性薬剤送達法の開発. リンパ学. 2016;39:25-7.

Zaini Z, Osuga M, Jimbo H, Yasuda J, Takagi R, Yoshizawa S, Umemura S. Study on heavy matching layer transducer towards producing second harmonics. Japanese Journal of Applied Physics. 2016;55:07KF15.

Yumita N, Watanabe T, Chen F, Momose Y, Umemura S. Induction of Apoptosis by Functionalized Fullerene-based Sonodynamic Therapy in HL-60 cells. Anticancer Res. 2016;36:2665-74.

Yoshizawa S, Matsuura K, Takagi R, Yamamoto M, Umemura S. Detection of tissue coagulation by decorrelation of ultrasonic echo signals in cavitation-enhanced high-intensity focused ultrasound treatment. Journal of therapeutic ultrasound. 2016;4:15.

Yasuda J, Yoshizawa S, Umemura S. Efficient generation of cavitation bubbles and reactive oxygen species using triggered high-intensity focused ultrasound sequence for sonodynamic treatment. Japanese Journal of Applied Physics. 2016;55:07KF24.

Tamano S, Jimbo H, Azuma T, Yoshizawa S, Fujiwara K, Itani K, Umemura S. Improvement of high-voltage staircase drive circuit waveform for high-intensity therapeutic ultrasound. Japanese Journal of Applied Physics. 2016;55:07KF17.

Takagi R, Jimbo H, Iwasaki R, Tomiyasu K, Yoshizawa S, Umemura S. Feasibility of real-time treatment feedback using novel filter for eliminating therapeutic ultrasound noise with high-speed ultrasonic imaging in ultrasound-guided high-intensity focused ultrasound treatment. Japanese Journal of Applied Physics. 2016;55:07KC10.

Taguchi K, Takagi R, Yasuda J, Yoshizawa S, Umemura S. Study on cavitation behavior during high-intensity focused ultrasound exposure by using optical and ultrasonic imaging. Japanese Journal of Applied Physics. 2016;55:07KF22.

Shimauchi A, Ota H, Machida Y, Yoshida T, Satani N, Mori N, Takase K, Tozaki M. Morphology evaluation of nonmass enhancement on breast MRI: Effect of a three-step interpretation model for readers’ performances and biopsy recommendations. Eur J Radiol. 2016;85:480-8.

Oyama S, Yasuda J, Hanayama H, Yoshizawa S, Umemura S. Quantitative measurement of ultrasound pressure field by optical phase contrast method and acoustic holography. Japanese Journal of Applied Physics. 2016;55:07KB9.

Osuga M, Yasuda J, Jimbo H, Yoshizawa S, Umemura S. Acceleration of lithotripsy using cavitation bubbles induced by second-harmonic superimposition. Japanese Journal of Applied Physics. 2016;55:07KF18.

Nakano N, Kato M, Itoh S. Regulation of the TMEPAI promoter by TCF7L2: the C-terminal tail of TCF7L2 is essential to activate the TMEPAI gene. J Biochem (Tokyo). 2016;159:27-30.

Mori N, Mugikura S, Takasawa C, Miyashita M, Shimauchi A, Ota H, Ishida T, Takase K, Kodama T, Takahashi S. Peritumoral apparent diffusion coefficients for prediction of lymphovascular invasion in clinically node-negative invasive breast cancer. Eur Radiol. 2016;26:331-9.

Mori N, Mugikura S, Takahashi S, Ito K, Takasawa C, Li L, Miyashita M, Kasajima A, Mori Y, Ishida T, Kodama T, Takase K. Quantitative Analysis of Contrast-Enhanced Ultrasound Imaging in Invasive Breast Cancer: A Novel Technique to Obtain Histopathologic Information of Microvessel Density. Ultrasound Med Biol. 2016.

Miura Y, Mikada M, Ouchi T, Horie S, Takeda K, Yamaki T, Sakamoto M, Mori S, Kodama T. Early diagnosis of lymph node metastasis: Importance of intranodal pressures. Cancer science. 2016.

Kuwahara Y, Miyazaki T, Shirosaki Y, Liu G, Kawashita M. Structures of organic additives modified magnetite nanoparticles. Ceramics International. 2016;42:6000-4.

Kodama T, Matsuki D, Tada A, Takeda K, Mori S. New concept for the prevention and treatment of metastatic lymph nodes using chemotherapy administered via the lymphatic network. Scientific Reports. 2016;6.

Kawashita M, Hasegawa M, Kudo T, Kanetaka H, Miyazaki T, Hashimoto M. Effect of fibronectin adsorption on osteoblastic cellular responses to hydroxyapatite and alumina. Materials Science and Engineering: C. 2016;69:1268-72.

Kawashita M, Endo N, Watanabe T, Miyazaki T, Furuya M, Yokota K, Abiko Y, Kanetaka H, Takahashi N. Formation of bioactive N-doped TiO2 on Ti with visible light-induced antibacterial activity using NaOH, hot water, and subsequent ammonia atmospheric heat treatment. Colloids Surf B Biointerfaces. 2016;145:285-90.

Kanetaka H, Liu G, Li Z, Miyazaki T, Furuya M, Kudo T, Kawashita M. TiO2 microspheres containing magnetic nanoparticles for intra‐arterial hyperthermia. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2016.

Kamitakahara M, Ohtoshi N, Kawashita M, Ioku K. Spherical porous hydroxyapatite granules containing composites of magnetic and hydroxyapatite nanoparticles for the hyperthermia treatment of bone tumor. J Mater Sci Mater Med. 2016;27:93.

Jimbo H, Takagi R, Taguchi K, Yoshizawa S, Umemura S. Advantage of annular focus generation by sector-vortex array in cavitation-enhanced high-intensity focused ultrasound treatment. Japanese Journal of Applied Physics. 2016;55:07KF19.

Iwase Y, Nishi K, Fujimori J, Fukai T, Yumita N, Ikeda T, Chen F, Momose Y, Umemura S. Antitumor effect of sonodynamically activated pyrrolidine tris-acid fullerene. Japanese Journal of Applied Physics. 2016;55:07KF2.

Iwasaki R, Takagi R, Nagaoka R, Jimbo H, Yoshizawa S, Saijo Y, Umemura S. Monitoring of high-intensity focused ultrasound treatment by shear wave elastography induced by two-dimensional-array therapeutic transducer. Japanese Journal of Applied Physics. 2016;55:07KF5.

Ichizuka K, Matsuoka R, Aoki H, Hasegawa J, Okai T, Umemura S. Basic study of less invasive high-intensity focused ultrasound (HIFU) in fetal therapy for twin reversed arterial perfusion (TRAP) sequence. Journal of Medical Ultrasonics. 2016;43:487-92.

Horie S, Suzuki Y, Kobayashi M, Kadonosono T, Kondoh S, Kodama T, Sato Y. Distinctive role of vasohibin-1A and its splicing variant vasohibin-1B in tumor angiogenesis. Cancer Gene Ther. 2016;23:133-41.

Hasegawa M, Kudo T, Kanetaka H, Miyazaki T, Hashimoto M, Kawashita M. Fibronectin adsorption on osteoconductive hydroxyapatite and non-osteoconductive α-alumina. Biomedical Materials. 2016;11:045006.

Fujita H, Kudo T, Kanetaka H, Miyazaki T, Hashimoto M, Kawashita M. Adsorption of Laminin on Hydroxyapatite and Alumina and the MC3T3-E1 Cell Response. ACS Biomaterials Science & Engineering. 2016;2:1162-8.

FUJIKAWA T, EGASHIRA R, FUJIKAWA S, TAKEDA K, KODAMA T. Extended Bernoulli equation, friction loss, and friction coefficient for microscopic Jeffery-Hamel flow with small Reynolds number up to O (1). Journal of Fluid Science and Technology. 2016;11:JFST0019-JFST.

Abe H, Mori N, Tsuchiya K, Schacht DV, Pineda FD, Jiang Y, Karczmar GS. Kinetic analysis of benign and malignant breast lesions with ultrafast dynamic contrast-enhanced MRI: comparison with standard kinetic assessment. Am J Roentgenol. 2016;207:1159-66.

2015

査読付論文

Hongu T, Funakoshi Y, Fukuhara S, Suzuki T, Sakimoto S, Takakura N, et al. Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial [beta] 1 integrin recycling. Nature communications. 2015;6.

Yoon J-H, Sudo K, Kuroda M, Kato M, Lee I-K, Han JS, et al. Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation. Nature communications. 2015;6.

Shiga K, Takahashi K, Sato I, Kato K, Saijo S, Moriya S, Hosono M, Miyagi T. Upregulation of sialidase NEU3 in head and neck squamous cell carcinoma associated with lymph node metastasis. Cancer Sci, 2015; 106(11) 1544-53.

M. Syahid, S. Oyama, J. Yasuda, S. Yoshizawa, and S. Umemura , "Quantitative measurement of high intensity focused ultrasound pressure field by optical phase contrast method applying non-continuous phase unwrapping algorithm" , Japanese Journal of Applied Physics, vol. 54, 07HC09, Jun. 2015.

Y. Iwase, N. Yumita, K. Nishi, H. Kuwahara, T. Fukai, T. Ikeda, F. Chen, Y. Momose, and S. Umemura , "Apoptosis induction by aluminum phthalocyanine tetrasulfonate-based sonodynamic therapy in HL-60 cells" , Japanese Journal of Applied Physics, vol. 54, 07HD05, Jun. 2015.

R. Takagi, K. Goto, H. Jimbo, K. Matsuura, R. Iwasaki, S. Umemura, and S. Yoshizawa , "Elimination of therapeutic ultrasound noise from pre-beamformed RF data in ultrasound imaging for ultrasound-guided high-intensity focused ultrasound treatment" , Japanese Journal of Applied Physics, vol. 54, 07HD10, Jun. 2015.

R. Nagaoka, R. Iwasaki, M Arakawa, K, Kobaayashi, S. Yoshizawa, S. Umemura, and Y. Saijo , "Basic study of intrinsic elastography: Relationship between tissue stiffness and propagation velocity of deformation induced by pulsatile flow" , Japanese Journal of Applied Physics, vol. 54, 07HF08, Jun. 2015.

X. Qu, T. Azuma, H Imoto, R, Raufy, H. Lin, H. Nakamura, S. Tamano, S. Takagi, S. Umemura, and I. Sakuma , "Novel automatic first-arrival picking method for ultrasound sound-speed tomography" , Japanese Journal of Applied Physics, vol. 54, 07HF10, Jun. 2015.

R. Iwasaki, R. Nagaoka, R. Takagi, K. Goto, S. Yoshizawa, Y. Saijo, and S. Umemura , "Effects of cavitation-enhanced heating in high-intensity focused ultrasound treatment on shear wave imaging" , Japanese Journal of Applied Physics, vol. 54, 07HF11, Jun. 2015.

K. Goto, R. Takagi, T. Miyashita, H. Jimbo S. Yoshizawa, and S. Umemura , "Effect of controlled offset of focal position in cavitation-enhanced high-intensity focused ultrasound treatment" , Japanese Journal of Applied Physics, vol. 54, 07HF12, Jun. 2015.

N. Sugita, M. Hosokawa, N, Sunaga, Y. Iwase, N. Yumita, T. Ikeda, and S. Umemura , "Sonodynamically-induced cytotoxicity by rose bengal derivative and microbubbles in isolated sarcoma 180 cells" , Japanese Journal of Applied Physics, vol. 54, 07HF16, Jun. 2015.

J. Yasuda, T. Miyashita, K. Taguchi, S. Yoshizawa, and S. Umemura , "Quantitative assessment of reactive oxygen sonochemically generated by cavitation bubbles" , Japanese Journal of Applied Physics, vol. 54, 07HF21, Jun. 2015.

S. Tamano, T. Azuma, S. Takagi, S. Umemura, and Y. Matsumoto , "Compensation of transducer element positions in a ring array ultrasonic computer tomography system" , Japanese Journal of Applied Physics, vol. 54, 07HF24, Jun. 2015.

S. Umemura , "Focused ultrasound transducer for thermal treatment" , International Journal of Hyperthermia, vol. 31, no. 2, pp. 216-221, Mar. 2015.

Z. Li, Y. Hong, J. Cao, Z. Huang, K Huang, H. Gong, L. Huang, S. Shi and M. Kawashita, Effects of mild alkali pretreatment and hydrogen-donating solvent on hydrothermal liquefaction of eucalyptus woodchips. Energy & Fuels, 2015;29(11):7335-42.

G. Liu, M. Kawashita, Z. Li, T. Miyazaki and H. Kanetaka, Sol-gel synthesis of magnetic TiO2 microspheres and characterization of their in vitro heating ability for hyperthermia treatment of cancer. Journal of Sol-Gel Science and Technology, 2015;75:90-97.

Tomita Y, Matsuura T, Kodama T. Temporal effect of inertial cavitation with and without microbubbles on surface deformation of agarose S gel in the presence of 1-MHz focused ultrasound. Ultrasonics, 2015;55:1-5.

Nagaoka R, Masuno G, Kobayashi K, Yoshizawa S, Umemura S, Saijo Y. Measurement of regional pulse-wave velocity using spatial compound imaging of the common carotid artery in vivo. Ultrasonics, 2015;55:92-103.

Kodama T, Hatakeyama Y, Kato S, Mori S. Visualization of fluid drainage pathways in lymphatic vessels and lymph nodes using a mouse model to test a lymphatic drug delivery system. Biomedical optics express, 2015;6:124-34.

Kawashita M, Tanaka Y, Ueno S, Liu G, Li Z, Miyazaki T. In vitro apatite formation and drug loading/release of porous TiO2 microspheres prepared by sol-gel processing with different SiO2 nanoparticle contents. Mater Sci Eng C Mater Biol Appl, 2015;50:317-23.

Kato Y, Yokoi T, Shin E, Kim IY, Kawashita M, Kikuta K, et al. Calcium phosphate-forming ability of magnetite and related materials in a solution mimicking in vivo conditions. Journal of Asian Ceramic Societies, 2015;3:44-9.

Kato S, Shirai Y, Kanzaki H, Sakamoto M, Mori S, Kodama T. Delivery of Molecules to the Lymph Node via Lymphatic Vessels Using Ultrasound and Nano/Microbubbles. Ultrasound Med Biol, 2015.

Azami S, Vo Nguyen TT, Watanabe Y, Kato M. Cooperative induction of transmembrane prostate androgen induced protein TMEPAI/PMEPA1 by transforming growth factor-β and epidermal growth factor signaling. Biochem Biophys Res Commun, 2015;456:580-5.

2014

査読付論文

Suenaga K, Kitahara S, Suzuki Y, Kobayashi M, Horie S, Sugawara J, et al. Role of the vasohibin family in the regulation of fetoplacental vascularization and syncytiotrophoblast formation. PLoS One. 2014;9:e104728.

Sakamoto M, Iikubo M, Kojima I, Sasano T, Mugikura S, Murata T, Watanabe M, Shiga K, Ogawa T, Takahashi S. Diagnostic value of capsule-like rim enhancement on magnetic resonance imaging for distinguishing malignant from benign parotid tumours. Int J Oral Maxillofac Surg. 2014 Sep;43(9):1035-41.

Sakashita T, Homma,A, Hayashi R, Kawabata K, Iwae S, Hasegawa Y, Nibu K, Kato T, Shiga K, Matsuura K, Monden N, Fujii M. The role of initial neck dissection for patients with node-positive oropharyngeal squamous cell carcinomas. Oral Oncol. 2014 Jul;50(7):657-61.

Yumita N, Iwase Y, Watanabe T, Nishi K, Kuwahara H, Shigeyama M, Sadamoto K, Ikeda T, Umemura S. Involvement of reactive oxygen species in the enhancement of membrane lipid peroxidation by sonodynamic therapy with functionalized fullerenes. Anticancer Res. 2014;34:6481-7.

Yasuda J, Miyashita T, Yoshizawa S, Umemura S. Effects of rose bengal on cavitation generation in gel phantom investigated using high-speed camera. Japanese Journal of Applied Physics. 2014;53:07KF20.

Vo Nguyen TT, Watanabe Y, Shiba A, Noguchi M, Itoh S, Kato M. TMEPAI/PMEPA1 enhances tumorigenic activities in lung cancer cells. Cancer Sci. 2014;105:334-41.

Sasaki S, Takagi R, Matsuura K, Yoshizawa S, Umemura S. Monitoring of high-intensity focused ultrasound lesion formation using decorrelation between high-speed ultrasonic images by parallel beamforming. Japanese Journal of Applied Physics. 2014;53:07KF10.

Sato T, Mori S, Arai Y, Kodama T. The combination of intralymphatic chemotherapy with ultrasound and nano-/microbubbles is efficient in the treatment of experimental tumors in mouse lymph nodes. Ultrasound Med Biol. 2014;40:1237-49.

Sasaki H, Yasuda J, Takagi R, Miyashita T, Goto K, Yoshizawa S, Umemura S. Highly efficient cavitation-enhanced heating with dual-frequency ultrasound exposure in high-intensity focused ultrasound treatment. Japanese Journal of Applied Physics. 2014;53:07KF11.

Nakano N, Maeyama K, Sakata N, Itoh F, Akatsu R, Nakata M, Katsu Y, Ikeno S, Togawa Y, Vo Nguyen T. T, Watanabe Y, Kato M, Itoh S. C18 ORF1, a novel negative regulator of transforming growth factor-β signaling. J Biol Chem. 2014;289:12680-92.

Miyazaki T, Tanaka T, Shirosaki Y, Kawashita M. Yttrium phosphate microspheres with enriched phosphorus content prepared for radiotherapy of deep-seated cancer. Ceramics International. 2014;40:15259-63.

Miyazaki T, Suda T, Shirosaki Y, Kawashita M. Fabrication of Yttrium Phosphate Microcapsules by Emulsion Route for In Situ Cancer Radiotherapy. Journal of Medical and Biological Engineering. 2014;34:14-7.

Miyazaki T, Inoue T, Shirosaki Y, Kawashita M, Matsubara T, Matsumine A. Bisphosphonate release profiles from magnetite microspheres. J Biomater Appl. 2014;29:543-7.

Miyasaka R, Yasuda J, Syahid M, Yoshizawa S, Umemura S. Quantitative measurement of focused ultrasound pressure field by background-subtracted shadowgraph using holographic diffuser as screen. Japanese Journal of Applied Physics. 2014;53:07KF24.

Kuwahara Y, Mori M, Kitahara S, Fukumoto M, Ezaki T, Mori S, et al. Targeting of tumor endothelial cells combining 2 Gy/day of X-ray with Everolimus is the effective modality for overcoming clinically relevant radioresistant tumors. Cancer Med. 2014;3:310-21.

Kuwahara Y, Miyazaki T, Shirosaki Y, Kawashita M. Effects of organic polymer addition in magnetite synthesis on the crystalline structure. RSC Advances. 2014;4:23359-63.

Kawashita M, Yokohama Y, Cui X, Miyazaki T, Kanetaka H. In vitro apatite formation and visible-light photocatalytic activity of Ti metal subjected to chemical and thermal treatments. Ceramics International. 2014;40:12629-36.

Kawashita M, Hayashi J, Li Z, Miyazaki T, Hashimoto M, Hihara H, et al. Adsorption characteristics of bovine serum albumin onto alumina with a specific crystalline structure. J Mater Sci Mater Med. 2014;25:453-9.

Kawashita M, Hayashi J, Kudo TA, Kanetaka H, Li Z, Miyazaki T, et al. MC3T3-E1 and RAW264.7 cell response to hydroxyapatite and alpha-type alumina adsorbed with bovine serum albumin. J Biomed Mater Res A. 2014;102:1880-6.

Iwase Y, Yumita N, Imaizumi T, Sakurazawa A, Kaya Y, Nishi K, Umemura S, et al. SONODYNAMICALLY INDUCED ANTICANCER EFFECTS BY FUNCTIONALIZED FULLERENES. Drug Metab Rev. vol. 45, no. S1, pp. 98, Jan. 2014.

Fukumoto M, Amanuma T, Kuwahara Y, Shimura T, Suzuki M, Mori S, et al. Guanine nucleotide-binding protein 1 is one of the key molecules contributing to cancer cell radioresistance. Cancer Sci. 2014;105:1351-9.

2013

査読付論文

Nakanome A, Brydun A, Matsumoto M, Ota K, Funayama R, Nakayama K, Ono M, Shiga K, Kobayashi T, Igarashi K. Bach1 is critical for the transformation of mouse embryonic fibroblasts by Ras(V12) and maintains ERK signaling. Oncogene. 2013 Jul 4;32(27):3231-45.

Kano S, Homma A, Hayashi R, Kawabata K, Yoshino K, Iwae S, Hasegawa Y, Nibu K, Kato T, Shiga K, Matsuura K, Monden N, Fujii M. Matched-pair analysis in patients with advanced oropharyngeal cancer: surgery versus concurrent chemoradiotherapy. Oncology. 2013;84(5):290-8.

Yumita N, Iwase Y, Imaizumi T, Sakurazawa A, Kaya Y, Nishi K, Ikeda T, Umemura S, et al. Sonodynamically-induced anticancer effects by functionalized fullerenes. Anticancer Res. 2013;33:3145-51.

Yoshizawa S, Yasuda J, Umemura S. High-speed observation of bubble cloud generation near a rigid wall by second-harmonic superimposed ultrasound. J Acoust Soc Am. 2013;134:1515-20.

Yokoi T, Kawashita M, Ohtsuki C. Effects of polymer concentration on the morphology of calcium phosphate crystals formed in polyacrylamide hydrogels. Journal of Crystal Growth. 2013;383:166-71.

Yokoi T, Kawashita M, Ohtsuki C. Biomimetic mineralization of calcium phosphates in polymeric hydrogels containing carboxyl groups. Journal of Asian Ceramic Societies. 2013;1:155-62.

Yokoi T, Kamitakahara M, Kawashita M, Ohtsuki C. Formation of organically modified octacalcium phosphate in solutions containing various amounts of benzenedicarboxylic acids. Journal of the Ceramic Society of Japan. 2013;121:219-25.

Harigane S, Miyasaka R, Yoshizawa S, Umemura S. Optical Phase Contrast Mapping of Highly Focused Ultrasonic Fields. Japanese Journal of Applied Physics. 2013;52:07HF.

Shishitani T, Matsuzawa R, Yoshizawa S, Umemura S. Changes in backscatter of liver tissue due to thermal coagulation induced by focused ultrasound. J Acoust Soc Am. 2013;134:1724-30.

Umemura S, Yoshizawa S, Takagi R, Inaba Y, Yasuda J. Enhancement of Focused Ultrasound Treatment by Acoustically Generated Microbubbles. Japanese Journal of Applied Physics. 2013;52:07HA2.

Shima H, Kawai T, Matsushima Y, Unuma H, Kawamura K, Li Z, Kawashita M. Magnetite fine particles highly loaded PMMA microspheres for hyperthermia of deep-seated cancer. Journal of the Ceramic Society of Japan. 2013;121:802-6.

Shibata H, Yokoi T, Goto T, Kim IY, Kawashita M, Kikuta K, et al. Behavior of hydroxyapatite crystals in a simulated body fluid: effects of crystal face. Journal of the Ceramic Society of Japan. 2013;121:807-12.

Shao L, Mori S, Yagishita Y, Okuno T, Hatakeyama Y, Sato T, Kodama T. Lymphatic mapping of mice with systemic lymphoproliferative disorder: usefulness as an inter-lymph node metastasis model of cancer. J Immunol Methods. 2013;389:69-78.

Sax N, Kodama T. Optimization of acoustic liposomes for improved in vitro and in vivo stability. Pharm Res. 2013;30:218-24.

Sakata N, Yoshimatsu G, Tsuchiya H, Aoki T, Mizuma M, Motoi F, Katayose Y, Kodama T, et al. Imaging of transplanted islets by positron emission tomography, magnetic resonance imaging, and ultrasonography. Islets. 2013;5:179-87.

Saito K, Mori S, Date F, Ono M. Sjögren's syndrome-like autoimmune sialadenitis in MRL-Faslpr mice is associated with expression of glucocorticoid-induced TNF receptor-related protein (GITR) ligand and 4-1BB ligand. Autoimmunity. 2013;46:231-7.

Okuno T, Kato S, Hatakeyama Y, Okajima J, Maruyama S, Sakamoto M, Mori S, Kodama T. Photothermal therapy of tumors in lymph nodes using gold nanorods and near-infrared laser light. J Control Release. 2013;172:879-84.

Okai T, Ichizuka K, Hasegawa J, Matsuoka R, Nakamura M, Shimodaira K, Sekizawa A, Kushima M, Umemura S. First successful case of non-invasive in-utero treatment of twin reversed arterial perfusion sequence by high-intensity focused ultrasound. Ultrasound Obstet Gynecol. 2013;42:112-4.

Nose M, Komori H, Miyazaki T, Mori S. Genomics of vasculitis: lessons from mouse models. Ann Vasc Dis. 2013;6:16-21.

Miyazaki T, Anan S, Ishida E, Kawashita M. Carboxymethyldextran/magnetite hybrid microspheres designed for hyperthermia. J Mater Sci Mater Med. 2013;24:1125-9.

Matsuyama S, Fujisawa M, Nagaya T, Ishii K, Terakawa A, Kikuchi Y, et al. Improvement of the energy stability of the Tohoku Dynamitron accelerator for microbeam and nanobeam applications. International Journal of PIXE. 2013;23:69-75.

Li Z, Miyazaki T, Kawashita M. Preparation and in vitro apatite-forming ability of porous and non-porous titania microspheres. Journal of the Ceramic Society of Japan. 2013;121:782-7.

Li L, Mori S, Sakamoto M, Takahashi S, Kodama T. Mouse model of lymph node metastasis via afferent lymphatic vessels for development of imaging modalities. PLoS One. 2013;8:e55797.

Li L, Mori S, Kodama M, Sakamoto M, Takahashi S, Kodama T. Enhanced sonographic imaging to diagnose lymph node metastasis: importance of blood vessel volume and density. Cancer Res. 2013;73:2082-92.

Nakamura K, Asai A, Sasaki H, Yoshizawa S, Umemura S. Large Volume Coagulation Utilizing Multiple Cavitation Clouds Generated by Array Transducer Driven by 32 Channel Drive Circuits. Japanese Journal of Applied Physics. 2013;52:07HF10.

Kochi T, Imai Y, Takeda A, Watanabe Y, Mori S, Tachi M, Kodama T. Characterization of the arterial anatomy of the murine hindlimb: functional role in the design and understanding of ischemia models. PLoS One. 2013;8:e84047.

Kawashita M, Nakamura K, Miyazaki T, Kanetaka H. Structure of Yttrium and Phosphorus-Containing Microspheres Prepared by Spray Dry Method. International Journal of Materials and Chemistry. 2013;3:16-20.

Kawashita M, Matsui N, Miyazaki T, Kanetaka H. Effect of Autoclave and Hot Water Treatments on Surface Structure and In Vitro Apatite-Forming Ability of NaOH- and Heat-Treated Bioactive Titanium Metal. MATERIALS TRANSACTIONS. 2013;54:811-6.

Kawashita M, Matsui N, Miyazaki T, Kanetaka H. Effect of ammonia or nitric acid treatment on surface structure, in vitro apatite formation, and visible-light photocatalytic activity of bioactive titanium metal. Colloids Surf B Biointerfaces. 2013;111:503-8.

Kanzaki H, Shinohara F, Kajiya M, Kodama T. The Keap1/Nrf2 protein axis plays a role in osteoclast differentiation by regulating intracellular reactive oxygen species signaling. J Biol Chem. 2013;288:23009-20.

Yasuda J, Asai A, Yoshizawa S, Umemura S. Efficient Generation of Cavitation Bubbles in Gel Phantom by Ultrasound Exposure with Negative-Followed by Positive-Peak-Pressure-Emphasized Waves. Japanese Journal of Applied Physics. 2013;52:07HF11.

Horie S, Chen R, Li L, Mori S, Kodama T. Contrast-enhanced high-frequency ultrasound imaging of early stage liver metastasis in a preclinical mouse model. Cancer Lett. 2013;339:208-13.

Asai A, Okano H, Yoshizawa S, Umemura S. Analysis of Temperature Rise Induced by High-Intensity Focused Ultrasound in Tissue-Mimicking Gel Considering Cavitation Bubbles. Japanese Journal of Applied Physics. 2013;52:07HF2.

Aoki H, Ichizuka K, Ichihara M, Matsuoka R, Hasegawa J, Okai T, Umemura S. Application of high-intensity focused ultrasound for fetal therapy: experimental study using an animal model of lower urinary tract obstruction. Journal of Medical Ultrasonics. 2013;40:107-10.

2012

査読付論文

Z. Li, M. Kawashita, T. Kudo and H. Kanetaka, "Sol-gel synthesis, characterization and in vitro compatibility evaluation of iron nanoparticle encapsulating-silica microspheres for hyperthermia of cancer", J. Mater. Sci.: Mater. Med., 23, 2461-2469 (2012). DOI

M. Kawashita, A. Kamitani, T. Miyazaki, N. Matsui, Z. Li, H. Kanetaka and M. Hashimoto, "Zeta potential of alumina powders with different crystalline structures in simulated body environments", Mater. Sci. Engin. C, 32, 2617-2622 (2012). DOI

Z. Li, K. Kawamura, M. Kawashita, T. Kudo, H. Kanetaka and M. Hiraoka, "In vitro heating capability, mechanical strength and biocompatibility assessment of PMMA-based bone cement containing magnetite nanoparticles for hyperthermia of cancer", J. Biomed. Mater. Res., 100A, 2537-2545 (2012). DOI

J. Hayashi, M. Kawashita, T. Miyazaki, M. Kamitakahara, K. Ioku and H. Kanetaka, "Comparison of adsorption behavior of bovine serum albumin and osteopontin on hydroxyapatite and alumina", Phosphorus Res. Bull., 26, 23-28 (2012). DOI

M. Kawashita, K. Taninai, Z. Li, K. Ishikawa and Y. Yoshida, "Preparation of low-crystalline apatite nanoparticles and their coating onto quartz substrates", J. Mater. Sci.: Mater. Med., 23, 1355-1362 (2012). DOI

T. Yokoi, H. Kato, I. Y. Kim, K. Kikuta, M. Kawashita and C. Ohtsuki, "Synthesis of octacalcium phosphate with incorporated succinate and suberate ions", Ceramics Int., 38, 3815-3820 (2012). DOI

A. S. Hamizah, M. Mariatti, R. Othman, M. Kawashita and A. R. Noor Hayati, "Mechanical and thermal properties of polymethylmethacrylate bone cement composites incorporated with hydroxyapatite and glass-ceramic fillers", J. Appl. Polym. Sci., 125, E661-669 (2012). DOI

T. Miyazaki, A. Miyaoka, E. Ishida, Z. Li, M. Kawashita and M. Hiraoka, "Preparation of ferromagnetic microcapsules for hyperthermia using water/oil emulsion as a reaction field", Mater. Sci. Engin. C, 32, 692-696 (2012). DOI

T. Yokoi, H. Kato, I. Y. Kim, K. Kikuta, M. Kamitakahara, M. Kawashita and C. Ohtsuki, "Formation of octacalcium phosphates with co-incorporated succinate and suberate ions", Dalton Trans., 41, 2732-2737 (2012). DOI

K. Takada, J. Okada, K. Nakamura, S. Yoshizawa, and S. Umemura, "High Voltage Staircase Drive Circuit for Triggered High-Intensity Focused Ultrasound Treatment," Japanese Journal of Applied Physics, vol. 51, pp. 07GF23 1-2, 2012.

K. Otsu, S. Yoshizawa, and S. Umemura, "Therapeutic Array Transducer Element Using Coresonance between Hemispherical Piezoceramic Shell and Water Sphere: Effect of Load Masses of Support and Electric Contact," Japanese Journal of Applied Physics, vol. 51, pp. 07GF24 1-6, 2012.

Y. Shimazaki, S. Harigane, S. Yoshizawa, and S. Umemura, "Three-Dimensional Quantitative Optical Measurement of Asymmetrically Focused Ultrasound Pressure Field," Japanese Journal of Applied Physics, vol. 51, pp. 07GF25 1-4, 2012. R. Matsuzawa, T. Shishitani, S. Yoshizawa, and S. Umemura, "Monitoring of Lesion Induced by High-Intensity Focused Ultrasound Using Correlation Method Based on Block Matching," Japanese Journal of Applied Physics, vol. 51, pp. 07GF26 1-6, 2012.

T. Moriyama, S. Yoshizawa, and S. Umemura, "Thermal Simulation of Cavitation-Enhanced Ultrasonic Heating Verified with Tissue-Mimicking Gel," Japanese Journal of Applied Physics, vol. 51, pp. 07GF27 1-6, 2012.

J. Shimizu, T. Fukuda, T. Abe, M. Ogihara, J. Kubota, A. Sasaki, T. Azuma, K. Sasaki, K. Shimizu, T. Oisih, S. Umemura and H. Furuhata, "Ultrasound Safety with Midfrequency Transcranial Sonothrombolysis: Preliminary Study on Normal Macaca Monkey Brain," Ultrasound in Medicine & Biology, vol. 38, no. 6, pp. 1040-1050, 2012.

K. Ichizuka, J. Hasegawa, M. Nakamura, R. Matsuoka, A. Sekizawa, T. Okai, amd S. Umemura, "High-intensity focused ultrasound treatment for twin reversed arterial perfusion sequence," ULTRASOUND IN OBSTETRICS & GYNECOLOGY, vol. 40, no. 4, pp. 476-478,2012.

N. Yumita, Y. Iwase, K. Nishi, K. Onodera, T. Fukai, T. Ikeda, S. Umemura, K. Okudaira and Y. Momose, "Involvement of Reactive Oxygen Species in Sonodynamically Induced Apoptosis Using a Novel Porphyrin Derivative,"THERANOSTICS, vol. 2, no. 9, pp. 880-888, 2012.

Y. MIURA, I. HIRAI, K. ISHII, S. MATSUYAMA, A. TERAKAWA, Y. KIKUCHI, M. FUJIWARA, H. SUGAI, S. HIRAISHI, A. FUKAYA, H. YAMAZAKI, T. TADA, K. SERA. PIXE ANALYSIS OF DYES USED IN TRADITIONAL JAPANESE CARPETS (NABESHIMA-DANTSU).[International Journal of PIXE,22(1 & 2),(2012),45-50].

H. SUGAI, K. FUJIKI, K. ISHII, S. MATSUYAMA, A. TERAKAWA, Y. KIKUCHI, M. FUJIWARA, Y. HATORI, N. HAMADA, Y. ITOH, S. HIRAISHI, Y. MIURA, A. FUKAYA, H. YAMAZAKI, T. TADA, E. SAKURAI. IMPROVEMENT OF THE DETECTION EFFICIENCY OF THE IN-AIR SUBMILLI-PIXE CAMERA FOR BIOLOGICAL APPLICATIONS.[International Journal of PIXE,22(1 & 2),(2012),37-43].

K. ISHII, A. TERAKAWA, S. MATSUYAMA, A. HASEGAWA, K. NAGAKUBO, T. SAKURADA, Y. KIKUCHI, M. FUJIWARA, H. YAMAZAKI, H. YUHKI, S. KIM, I. SATOH. MEASURES AGAINST RADIOACTIVE CONTAMINATION DUE TO FUKUSHIMA FIRST NUCLEAR POWER PLANT ACCIDENTS PART III: REMOVING AND DECONTAMINATION OF CONTAMINATED SOIL. [International Journal of PIXE,22(1 & 2),(2012),13-19].

K. ISHII, A. TERAKAWA, S. MATSUYAMA, A. HASEGAWA, K. NAGAKUBO, T. SAKURADA, Y. KIKUCHI, M. FUJIWARA, H. YAMAZAKI, H. YUHKI, S. KIM, I. SATOH. MEASURES AGAINST RADIOACTIVE CONTAMINATION DUE TO FUKUSHIMA FIRST NUCLEAR POWER PLANT ACCIDENTS PART II: MEASUREMENT OF SPACE RADIATION DOSE RATES AND EXAMINATION OF CONTAMINATION IN FOOD.[International Journal of PIXE,22(1 & 2),(2012),7-12].

K. ISHII, A. TERAKAWA, S. MATSUYAMA, A. HASEGAWA, K. NAGAKUBO, T. SAKURADA, Y. KIKUCHI, M. FUJIWARA, H. YAMAZAKI, H. YUHKI, S. KIM, I. SATOH. MEASURES AGAINST RADIOACTIVE CONTAMINATION DUE TO FUKUSHIMA FIRST NUCLEAR POWER PLANT ACCIDENTS PART I: DAMAGE SITUATION OF THE GREAT EAST JAPAN EARTHQUAKE.[International Journal of PIXE,22(1 & 2),(2012),1-5].

Terakawa A., Ishii K., Matsuyama S., Kikuchi Ito Y., Yasunaga S., Tagawa A., Kawamura T., Takahashi Y., Hatori Y., Hamada N., Fujiki K., Miura Y., Yamazaki H., Funaki Y., Itoh N., Wada S. and Sera K. A Preliminary Study of Proton Therapy Combined with Cisplatin.[CYRIC Annual Report 2010-2011,(2012),46-48].

Matsuyama S., Catella G., Ishii K., Terakawa A., Kikuchi Y., Kawamura Y., Ohkura S., Fujikawa M., Hamada N., Fujiki K., Hatori Y., Ito Y., Yamazaki H., Hashimoto Y., Zitnik M., Pelicon P., and Grlj N. Microbeam Analysis of Individual Particles in Working Environment.[CYRIC Annual Report 2010-2011,(2012),57-61].

Terakawa A., Ishii K., Matsuyama S., Kikuchi Y., Yasunaga S., Ito Y., Tagawa A., Kawamura T., Takahashi Y., Sugai H., Hamada N., Fujiki K., Hatori Y., Yamazaki H., Funaki Y., Furumoto S., Itoh N. and Wada S. PIXE Analysis of a Murine Fibrosarcoma Tumor Treated With a Vasucular Disrupting Agent AVE8062.[CYRIC Annual Report 2010-2011,(2012),49-51].