HIRANO LAB RIEC/AIMR, Tohoku University

Nano-Bio Hybrid Molecular Devices Laboratory

Creation of artificial cell membrane system by fusion of
biomolecules and Nano/Micro-Fabrication

Ayumi Hirano-Iwata
Professor

Our laboratory aims to construct functional biodevices and systems by integrating nanotechnology and microfabrication techniques cultivated in the field of electronics with various biomaterials such as cell membranes, membrane proteins, and neurons.
To this end, we are working daily to create new medical and electronic devices that utilize the properties of these biomolecules, and to construct new experimental systems to investigate the principles of information processing in the cranial nervous system.

  • Research theme ①

    Sensing of Adverse Effects of Candidate Drugs and Development of Tailored Medicine

    Using the device shown above, we hope to create a sensor that can rapidly detect the side effects of candidate drugs, which will be useful for future tailor-made medicine.

  • Research theme ②

    Creation of photoreactive nanobiodevices

    As applied research using artificial cell membranes, we are also working on the creation of completely new nano-bio hybrid devices that respond to external light.

  • Research theme ③

    Construction of cultured neuronal networks

    We are also conducting research to understand how the brain processes information by constructing neural circuits by arranging nerve cells on a substrate and examining their functions.

News

2023.8
A paper on ion channel-based sensor was published in Biophysical Journal
2023.8
A paper on nanobubbles was published in Journal of Colloid and Interface Science
2023.8
A paper on microfabricated neuronal networks was published in Science Advances
2023.7
A review on microfabricated neuronal networks was published in JSAP Review
2023.6
A paper on microfabricated neuronal networks was published in PNAS
2023.5
A review on microfabricated neuronal networks was published in Oyo Buturi
2023.1
A paper on microfabricated neuronal networks was published in Frontiers in Neuroscience
2022.9
A review on ion channel-based sensor was published in Membranes
2022.5
Assoc. Prof. Hideaki Yamamoto received JSAP M&BE Paper Award
2022.3
A paper on gas sensor was published in Sensors and Actuators B
2021.9
A paper on ion channel-based sensor was published in Faraday Discussions
2021.8
A paper on nanobubbles was published in Langmuir
2021.4
A paper on microfabricated neuronal networks was published in Electrochemistry
2021.4
A paper on liposome manipulation was published in OSA Technical Digest (Optica Publishing Group)
2018.1
A review on ion channel-based sensor was published in JJAP
2017.12
A paper on ion channel-based sensor was published in Scientific Reports
2017.11
A paper on organic solar cells was published in Organic Electronics
2016.7
A paper on microfabricated neuronal networks was published in APL
2016.7
A paper on microfabricated neuronal networks was published in PRE
2016.5
A paper on the ion channel-based sensor was published in BJ
2016.4
Daisuke's paper on a novel organic transistor was published in JAP
2016.4
New homepage!
2016.1
Ryosuke's paper on a glial cell sheet was published in APL
2015.11
Ayumi received the RIEC Award
2014.10
Launched a JST-CREST Program: Construction of ion and electron nano-channels in super-resistive lipid bilayers

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